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KMID : 1141520180330010114
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Endocrinology and Metabolism
2018 Volume.33 No. 1 p.114 ~ p.120
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A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications
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Jeong Eun-Ji
Chung Sae-Rom
Baek Jung-Hwan
Choi Young-Jun
Kim Jae-Kyun
Lee Jeong-Hyun
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Abstract
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Background: To compare pain, tolerability, and complications associated with fine needle aspiration (FNA) versus core needle biopsy (CNB).
Methods: FNAs were performed using 23-gauge needles and CNBs were performed using 18-gauge double-action spring-activated needles in 100 patients for each procedure. Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability. Complications and number of biopsies were recorded.
Results: The median pain scores were similar for the FNA and CNB approaches during and 20 minutes after the biopsy procedures (3.7 vs. 3.6, P=0.454; 0.9 vs. 1.1, P=0.296, respectively). The procedure was tolerable in all 100 FNA patients and in 97 CNB patients (P=0.246). The mean number of biopsies was fewer in the CNB group (1.4 vs. 1.2, P=0.002). By subgroup analysis (staff vs. non-staff), no significant difference was detected in any parameter. There were no major complications in either group, but three patients who underwent CNB had minor complications (P=0.246).
Conclusion: FNA and CNB show no significant differences for diagnosing thyroid nodules in terms of pain, tolerability, or complications.
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KEYWORD
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Thyroid nodule, Biopsy, fine-needle, Biopsy, large-core needle, Safety
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